The Obesity Epidemic.

most frequently asked questions is what they should eat. Ms Karina Knight-Sepulveda, Dr Susan Kais, Dr Rebeca Santaolalla, and Dr Maria T. Abreu explore diets commonly recommended to IBD patients—such as the low–fermentable oligosaccharide, disaccharide, monosaccharide, and polyol diet; the specific carbohydrate diet; the anti-inflammatory diet; and the Paleolithic diet—and review the data currently available on them. Our IBD coverage continues with a discussion of very–early-onset IBD (VEOIBD) in our Advances in IBD column. Dr Scott B. Snapper explains how understanding this condition is leading to novel therapeutic approaches that can be used in both children and adults with IBD. In our Advances in Hepatology column, Dr Stuart C. Gordon provides an overview of polycystic liver disease, with a focus on treatment options and recent literature findings. Our other two standard monthly columns provide valuable images in the exploration of their topics. In our Advances in GERD column, Dr Robert M. Genta discusses lymphocytic esophagitis and supplies images of endoscopic and histopathologic findings of this condition. In our Advances in Endoscopy column, Dr Richard A. Kozarek examines a novel endoscopic approach to reopening a completely obstructed esophagus and provides a series of images depicting the steps of the procedure. In addition, our HCC in Focus column returns this month with an interview with Dr Richard S. Finn on the treatment of intermediate-stage hepatocellular carcinoma. Various treatment options are discussed, including chemoembolization performed with ethiodized oil (Lipiodol, Guerbet) or doxorubicin-loaded beads, and sorafenib (Nexavar, Bayer/Onyx) therapy. I hope you find this issue interesting and informative.